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Low-Dose Alternate-Day Prednisone for Persistent Wells' Syndrome
Brett M. Coldiron, MD;
June K. Robinson, MD
Arch Dermatol. 1989;125(12):1625-1626.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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REPORT OF A CASE
A 26-year-old white female was initially diagnosed as having Wells' syndrome (eosinophilic cellulitis) in 1979, and was described in the literature in 1984.1 She gave no history of insect bites or chemical exposure. During the last 10 years she has had multiple episodes of recurrent swollen, weeping, erythematous plaques that occurred mainly on the face (Figure), but that also arose on the upper extremities and shoulders. These plaques resolved, first with central clearing, after 2 to 3 weeks. Occasionally these plaques developed bullae on a firm indurated base. Histopathologically, her skin biopsy specimens show characteristic eosinophilic infiltrates, with some lymphocytes and histiocytes, edema surrounding dermal blood vessels, and flame figures. She was also noted to have a peripheral eosinophilia of up to 8%. She has had repeated normal blood cell counts (except for the eosinophilia noted above), and has had normal examination results for stool ova
. . . [Full Text PDF of this Article]
Author Affiliations
University of Cincinnati (Ohio) Medical Center; Northwestern University Medical School, Chicago, Ill
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