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A Unifying Concept

Paul G. Norris, MRCP; John L. M. Hawk, FRCP

Arch Dermatol. 1990;126(3):376-378.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Persistent light reactivity, photosensitive eczema, photosensitivity dermatitis, or actinic reticuloid? Increasing experience indicates that these syndromes (Table), which were defined 15 or more years ago and generally occur in elderly men, represent arbitrary, confusing, and largely unnecessary subclassifications, and in this issue of the ARCHIVES Lim et al¹ rightly suggest that the conditions should be considered as variants of a single condition, namely chronic actinic dermatitis.

The syndrome of persistent light reactivity was first recognized in 1962 by Wilkinson² after an epidemic of photoallergy to tetrachlorosalicylanilide, an antibacterial agent incorporated into soaps and hair toiletries. Following an episode of photoallergy caused by epicutaneous contact with a photoallergen such as one of these halogenated salicylanilides, musk ambrette³ or quinoxaline dioxide,⁴ some subjects develop persistent photosensitivity of both exposed and covered skin despite removal of the offending chemical from the environment. Whereas the action spectrum for the initiating . . . [Full Text PDF of this Article]

Author Affiliations
Photobiology Unit Institute of Dermatology United Medical and Dental Schools of Guy's and St Thomas' Hospital St Thomas Hospital London SE1 7EH, England

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