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Jo L. Herzog, MD; F. Mack Sexton, MD

Arch Dermatol. 1990;126(6):817-818.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

We evaluated an eruption in a 61-year-old woman with scleroderma complicated by chronic renal failure. The patient also had metastatic breast carcinoma and was being treated with combination therapy that included systemic steroids. A few days prior to dermatologic evaluation, the patient was admitted for nausea, fever, and malaise. She was found to have a left-sided pleural effusion, which was drained and cultured, yielding microorganisms. Therapy with nafcillin and gentamicin was started.

On the third day after hospital admission, a "rash" was noted. The patient had generalized erythema and peeling of the skin over the forearms, over areas where tape had been applied, and over the perioral and perirectal areas (Figs 1 and 2). These areas exhibited Nikolsky's sign. There were no intact bullae. The patient also had periorbital edema with a purulent discharge from both eyes. Her skin was tender to touch.

A frozen . . . [Full Text PDF of this Article]

Author Affiliations
College of Medicine/University Hospital, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey

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