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Arch Dermatol. 1990;126(7):859-860.

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BECAUSE the prevalence of antimicrobial resistance in Neisseria gonorrhoeae increased during the early 1980s,¹ in 1986 CDC implemented the Gonococcal Isolate Surveillance Project (GISP) to monitor antimicrobial susceptibilities at 21 collaborating sexually transmitted disease clinics in 21 cities.² Each month, isolates from the first 20 men^* with urethral gonococcal infections at each clinic are submitted to one of four regional laboratories for susceptibility testing. This report describes the results of surveillance for plasmid-mediated resistance in N. gon-orrhoeae in 1988 and 1989.

During these 2 years, 9309 gonococcal isolates (4620 in 1988 and 4689 in 1989) were collected from the 21 clinics. Strains were isolated primarily from black (76.6%), heterosexual (95.9%) men; the median age of the men was 25 years.

The susceptibilities (minimum inhibitory concentrations [MICs]) to penicillin, tetracycline, spectinomycin, and ceftriaxone were determined for each isolate. The definitions of susceptibility to these antimicrobial agents are those . . . [Full Text PDF of this Article]

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