This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (35)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Serge A. Coopman, MD; Robert S. Stern, MD

Arch Dermatol. 1991;127(5):714-717.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In this issue of the ARCHIVES, Porteous and Berger¹ describe eight individuals with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) who experienced severe cutaneous adverse reactions to drugs, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Also in this issue, Garty² reports such a case. These adverse events, which were seen in individuals who received multiple medications, occurred from 1 to 21 days (median, 8 days) after therapy with the suspect drug was initiated. Five patients had had a history of prior maculopapular drug eruptions, and two of them had had a previously documented reaction to the suspect drug. In three of these eight cases sulfonamides were suspected. As suggested in this report, other drugs appear to be causes of these reactions as well, but the magnitude of this risk with other drugs is far less clear. The authors note that patients with AIDS and toxoplasmosis . . . [Full Text PDF of this Article]

Author Affiliations
Department of Dermatology Harvard Medical School Boston, MA 02215

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?