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Bullous Eruption in an Infant
A. J. G. Mc Donagh, MB, ChB, MRCP;
A. G. Messenger, MD, MRCP;
B. L. Priestley, MD, BS, FRCP
Arch Dermatol. 1991;127(7):1051-1052.
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REPORT OF A CASE
A 5-month-old girl was admitted to the hospital with a 36-hour history of large tense blisters on the trunk. For 2 weeks before this event, the child's mother had noticed intermittent blotchiness of the skin. The child's birth and developmental history were normal, her mother was in good health, and the child did not receive any drugs before the onset of the eruption. Her maternal uncle had a history of a widespread rash present since infancy but had never suffered from blistering.
Physical examination revealed an extensive eruption of tense bullae, mainly on the trunk (Fig 1). Some of the lesions were hemorrhagic. The remainder of the physical examination was unremarkable. A skin biopsy specimen was obtained at the site of a bullous lesion on the abdominal wall (Figs 2 through 4). Histologic examination revealed a dense cellular infiltrate in the upper third of the dermis
. . . [Full Text PDF of this Article]
Author Affiliations
Royal Hallamshire Hospital and Children's Hospital, Sheffield, England
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