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  Vol. 127 No. 9, September 1991 TABLE OF CONTENTS
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Ichthyosis, Exocrine Pancreatic Insufficiency, Impaired Neutrophil Chemotaxis, Growth Retardation, and Metaphyseal Dysplasia

Chrinstopher P. Schmidt, MD
Department of Dermatology The Johns Hopkins Medical Institutions 600 N Wolfe St Baltimore, MD 21205

Arch Dermatol. 1991;127(9):1417-1418.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Recently, Goeteyn and coworkers1 published a case report on the Schwachman syndrome and suggested that skin findings are frequently a component of this syndrome.

What caught my eye in this article were the statements that essential fatty acid (EFA) deficiency and red scaly eruptions have not been reported in cystic fibrosis. In fact, there are several publications describing each of these in patients with cystic fibrosis.2-4 In addition, my own experience suggests this is not a rare occurrence.5

It is thought that the pancreatic exocrine dysfunction seen in cystic fibrosis causes multiple nutritional deficiencies.2 These include decreased serum zinc, protein, and EFA concentrations. Each deficiency can cause a red scaly eruption. Dietary supplementation, including pancreatic enzymes, results in rapid resolution of the dermatitis.

The patient described by Goeteyn et al had pancreatic dysfunction similar to that found in cystic fibrosis. He also . . . [Full Text PDF of this Article]



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