REPORT OF A CASE
A 60-year-old woman with a history of deep venous thrombosis was referred for evaluation of "persistent superficial thrombophlebitis." Six months before admission, tender red areas developed initially on her thighs and subsequently spread to her abdomen. Otherwise, she was in excellent health.
Her physical examination showed normal findings except for her skin, where large areas of induration were seen on both thighs and the lower abdomen (Fig 1). Overlying the indurated areas were numerous partially blanching, arborizing superficial telangiectasias (Fig 2). Pitting edema without telangiectasias was present below the knees.
Abnormal laboratory findings included the following: hematocrit, 0.27; erythrocyte sedimentation rate, 111 mm/h; and lactate dehydrogenase, 1141 U/L (normal, 230 to 450 U/L). Normal laboratory findings included the following results: serum electrolytes, leukocytes, platelets, prothrombin time, partial thromboplastin time, aspartate aminotransferase, and alanine aminotransferase.
A skin biopsy was performed and the specimen sent for histopathologic
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