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Elaine T. Kaye, MD; Irvin H. Blank, PhD; R. Rox Anderson, MD; Kenneth A. Arndt, MD; Jay A. Levin, MD
Department of Dermatology Wellman Laboratories of Photomedicine Massachusetts General Hospital Boston, MA 02114; Department of Dermatology Beth Israel Hospital Boston, MA 02215; 1293 Peachtree St NE, Suite 212 Atlanta, GA 30307

Arch Dermatol. 1992;128(3):409.

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In Reply.—

The use of dihydroxyacetone (DHA) is a timehonored method for cosmetic "sunless tanning" by producing an orange-brown oxidation product within the stratum corneum.¹ Johnson's interesting work on UV-A photoprotection by this absorption-type sunscreen is clinically important.² Dihydroxyacetone/naphthoquinone chemically altered stratum corneum absorbs UV-A and blue visible light.³ Our study⁴ shows that the interaction of light scattering with light absorption can provide photoprotection more effectively than either process independently; it is interesting to speculate how epidermal scattering may enhance the effectiveness of dihydroxyacetone as a UV-A—visible sunscreen, in comparison with typical surface-layer sunscreens. We certainly appreciate this well-informed response to our article. . . . [Full Text PDF of this Article]

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