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A STUDY OF TOXICITY, ABSORPTION, ELIMINATION AND SPIROCHETICIDAL POWER

O. M. GRUHZIT, M.S., M.D.

Arch Derm Syphilol. 1926;13(2):195-214.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A great number of research workers in this country and abroad are devoting their time to finding new and better antisyphilitic drugs. Recently, Sazerac and Levaditi¹ demonstrated spirocheticidal activity of bismuth in experimental and clinical syphilis. Fournier and Guenot² followed the initial reports of Sazerac and Levaditi with extensive clinical observations on 200 syphilitic patients. Since these reports the literature abounds with reports of favorable clinical action of bismuth in the treatment of syphilis.

In this country, McCafferty,³ Pardo-Castello⁴ (Cuba), Hopkins,⁵ and Klauder⁶ have presented clinical and experimental findings. In France, Sazerac and Levaditi,¹ Levaditi,⁷ Fournier and Guenot,² and in Germany, Kolle,⁸ Bieder,⁹ and Giemsa¹⁰ have given extensive reviews of the literature as well as their own clinical and experimental findings.

The use of bismuth in the treatment of syphilis by Masucci¹¹ dates back to 1899. Syphilitic . . . [Full Text PDF of this Article]

Author Affiliations
From the Medical Research Laboratories, Parke, Davis & Company.

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