This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Alan R. Shalita, MD

Arch Dermatol. 1994;130(3):363-364.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE STUDY by Lucky et al¹ in this issue of the ARCHIVES clearly confirms the observation that acne may be the earliest sign of puberty. This investigation, as well as other recent publications, identifies adrenal androgen as a significant factor in prepubertal acne. Furthermore, since adrenarche precedes menarche, early acne is associated with, and a marker of, adrenarche. Finally, Lucky et al have contributed significantly to our understanding of the role of adrenal androgens in early acne. One can reasonably hope that a better understanding of the initial stages of acne may lead to superior intervention at a younger age with the expectation that one may then prevent the subsequent evolution of this stubborn and troublesome disease.

Androgens have been known to play a role in the pathogenesis of acne since the early 1940s when J. B. Hamilton described ''male hormone substance'' as a factor in acne. Since then . . . [Full Text PDF of this Article]

Author Affiliations
Department of Dermatology State University of New York—Brooklyn Health Science Center 450 Clarkson Ave, Box 46 Brooklyn, NY 11203

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?