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Woolly Hair, Palmoplantar Keratoderma, and Cardiac Abnormalities: Report of a Family
Antonella Tosti, MD
Istituto di Clinica Dermatologica Università degli Studi di Bologna Via Massarenti, 1 40138 Bologna, Italy
Cosimo Misciali, MD;
Bianca Maria Piraccini, MD;
Pier Alessandro Fanti, MD
Bologna, Italy
Mauro Barbareschi, MD
Milan, Italy
Rossella Maria Ferretti, MD
Bologna, Italy
Arch Dermatol. 1994;130(4):522-524.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Hereditary woolly hair has occasionally been associated with abnormalities of the skin,1 eyes, and ears. Barker et al2 have recently reported seven families in Greece affected by a new autosomal recessive syndrome characterized by the asso- ciation of woolly hair, palmoplantar keratoderma, and cardiac abnormalities.2
We describe two members of a family who presented a similar, but not identical, condition.
Report of Cases.
Case 1. A 20-year-old electrician was admitted to our clinic in June 1991 for a palmoplantar keratoderma. His history revealed that the plantar keratoderma had been present since the age of 1 year and had progressively worsened during the years. Palmar hyperkeratosis first appeared at the age of 17, when the patient started his job as an electrician.
The clinical examination revealed a very thick, yellow hyperkeratosis over the pressure areas of the patient's palms and soles (Figure 1). Painful hyperkeratotic lesions of the
. . . [Full Text PDF of this Article]
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