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Gunter Burg, MD
Dermatologische Klinik Universitatsspital Zurich Gloriastrasse 31 CH 8091 Zurich, Switzerland

Reinhard Dummer, MD; Frank Nestle, MD
Zurich, Switzerland

Arch Dermatol. 1994;130(8):1073.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It was with great interest that I read the article by Perniciaro et al¹ on subcutaneous T-cell lymphoma. The authors made some statements on which I would like to comment.

The authors are correct in pointing out that there are two distinct clinical presentations, one characterized by a protracted course of recurrent self-healing subcutaneous nodules and another by a clinical course that rapidly progresses.

However, there seem to be additional subtypes that should not be intertwined. The cases reported by Gonzalez et al² and us³ differ in many respects, such as delta-positivity, lack of cytophagia, production of interferon gamma, and slow progression of disease. In the case we reported, death, indirectly related to the lymphoma (leukopenia, fever), occurred within 5 years.³

In conclusion, the subcutaneous localization of the infiltrate, by itself, is not a distinct feature characterizing a nosologic subtype of lymphoma but a histologic phenotype, . . . [Full Text PDF of this Article]

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