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Mira Pavlovic, MD
Boulogne

Philippe Saiag, MD
Service de Dermatologie Hôpital Ambroise Paré Université Paris V 92104 Boulogne, France

Jean-Pierre Lotz, MD; Edouardo Marinho, MD
Paris, France

Thierry Clerici, MD
Boulogne

Victor Izrael, MD
Paris

Arch Dermatol. 1995;131(10):1207-1209.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The principal skin manifestations of carcinoid syndrome are flush, acral pigmentation, cyanosis, and facial telangiectases. We describe herein a patient with carcinoid syndrome whose sclerodermatous lesions of the lower legs, an infrequent manifestation of this syndrome, have entirely subsided with chemotherapy and administration of the long-acting somatostatin analogue octreotide.

Report of a Case.

A 51-year-old white man was admitted in October 1990 for abdominal pain, diarrhea, and weight loss. On clinical examination, a metastatic liver, ascites, edema of the legs, and failure of the right side of the heart were found. The liver biopsy specimen revealed a poorly differentiated metastatic carcinoma whose origin was initially unknown. The first 5-day course of alternate chemotherapy was administered as follows: fluorouracil, 375 mg/m² daily; folinic acid, 200 mg/m² daily; and cisplatin, 15 mg/m² daily, alternated with streptozotocin, 500 mg/m² daily.

In December 1990, the patient was referred to the . . . [Full Text PDF of this Article]

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