This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Anthony J. Meyer; George T. Nahass, MD

Arch Dermatol. 1995;131(12):1447-1448.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

A 24-year-old man presented complaining of abnormal skin pigmentation on the dorsa of his feet that had been present for 2 years and was becoming progressively worse. He denied any trauma to the area, but was an active windsurfer and snow skier. His inflammatory acne had been treated over the past 6 years with minocycline (orally, 100 mg/d), tretinoin, and topical benzoyl peroxide with erythromycin (Benzamycin).

On physical examination, the lesions were symmetric 4x6-cm gray-blue patches on the dorsa of both feet (Figure 1). The pigmentation was localized to the distribution of the extensor digitorum brevis muscle, which was hypertrophied. No mucosal, periungual, or other abnormal cutaneous pigmentation was seen. A 4-mm punch biopsy specimen was obtained down to the skeletal muscle and stained with hematoxylin-eosin (Figure 2), Prussian blue (Figure 3), and Fontana-Masson (Figure 4).

What is your diagnosis?

DIAGNOSIS:

Minocycline pigmentation. . . . [Full Text PDF of this Article]

Author Affiliations
St Louis University Medical Center, St Louis, Mo

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?