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Akira Ishiko, MD; Takashi Hashimoto, MD; Hiroshi Shimizu, MD; Takuji Masunaga, MPh; Yukiko Nishibori, MD; Kyoko Watanabe, MD; Takeji Nishikawa, MD
Department of Dermatology Keio University School of Medicine 35 Shinanomachi Shinjuku Tokyo 160, Japan

Arch Dermatol. 1995;131(6):732-734.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Pemphigus foliaceus (PF) and bullous pemphigoid (BP) are blistering skin diseases caused by autoantibodies against the keratinocyte cell surface or the basement membrane zone (BMZ) of the epidermis, respectively. These diseases rarely coexist, with only three such cases reported.^1-3 However, none has been studied by immunoelectron microscopy. In only one case was immunoprecipitation used to confirm the coexistence at the molecular level.³ We report coexistent PF and BP, in which a reactivity of the autoantibodies was studied by both immunoblot and immunoelectron micro scopic examination.

Report of a Case.

A 63-year-old Japanese man visited us complaining of blisters and erosions that involved almost the entire body. He had noticed crusted erythema on his back and had been treated under a diagnosis of PF for 6 years until tense vesicles and blisters developed rapidly on the trunk and extremities 3 months before his presenttion. Physical examination showed erythema with . . . [Full Text PDF of this Article]

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