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John L. Snow, MB, ChB; Mark J. Zalla, MD; Randall K. Roenigk, MD; Lawrence E. Gibson, MD

Arch Dermatol. 1995;131(9):1069-1070.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

A 68-year-old man presented with a 1-month history of change within a lifelong lesion on his left cheek.

The patient reported the growth of a new nodule, which he had noticed bled with minimal trauma.

Examination revealed a 1.5x1.0-cm poorly marginated, reddish, and somewhat translucent nodule arising within a 3-cm linear, orange yellow plaque that had a cobblestonelike texture (Figure 1). A biopsy specimen was taken (Figure 2). Tissue from the subsequent excision was also examined microscopically (Figure 3).

What is your diagnosis?

DIAGNOSIS:

Squamous cell carcinoma arising in a nevus sebaceus of Jadassohn (NSJ).

HISTOPATHOLOGIC FINDINGS AND CLINICAL COURSE

The biopsy specimen of the nodular lesion showed an infiltrating, keratinizing, epithelioid tumor arising from the epidermis. There was a moderately intense lymphocytic inflammatory response surrounding the tumor. The subsequent excision specimen revealed a dilated follicular infundibulum filled with keratinous material, subtle . . . [Full Text PDF of this Article]

Author Affiliations
Mayo Clinic and Mayo Foundation, Rochester, Minn

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