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  Vol. 131 No. 9, September 1995 TABLE OF CONTENTS
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Ulcers in Pretibial Epidermolysis Bullosa

Grafting With Autologous Meshed Split-Thickness Skin and Allogeneic Cultured Keratinocytes

Hilde Beele, MD, PhD; Jean-Marie Naeyaert, MD, PhD; Stan Monstrey, MD, PhD; André Kint, MD, PhD

Arch Dermatol. 1995;131(9):990-992.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

In 1973, a 52-year-old woman presented with numerous lichenoid plaques and papules and a few flaccid bullae on both knees and the pretibial zones (Figure 1). A few isolated papules were also seen. All toenails were dystrophic. The patient suffered from extreme pruritus. While erythematous plaques were present on her knees since the age of 11 years, the clinical picture became dramatically more severe after the patient reached the age of 50.1 The patient denied the presence of similar lesions in family members.

In 1989, the clinical picture became dominated by the presence of multiple ulcers of various sizes on the pretibial areas (Figure 2). The ulcers were surrounded by a fragile, poikilodermatous skin. During hospitalization, bullae appeared after minor trauma. These nonhealing bullae continuously resulted in multiple ulcers.

Histologic analysis of a fresh blister by light and electron microscopy and immunohistologic studies with bullous . . . [Full Text PDF of this Article]


Author Affiliations

University Hospital, Gent, Belgium



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