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Hepatitis C Virus Infection and Porphyria Cutanea Tarda in Australasia
Paul Salmon;
Amanda Oakley;
Marius Rademaker;
Mark Duffill
Department of Dermatology Waikato Hospital New Zealand
Arch Dermatol. 1996;132(1):91.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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In the last 2 years, there has been interest in the relationship between hepatitis C virus (HCV) infection and porphyria cutanea tarda (PCT). Accordingly, we were concerned with identifying any of our patients with PCT who may have HCV infection so as to offer counseling and treatment. Patients known to suffer from PCT were contacted through outpatient appointments or by correspondence and were asked to provide a serum specimen for HCV analysis and measurement of alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, -glutamyltransferase, protein, and albumin concentrations, and for a complete blood cell count. Of the 25 patients traced, none were found to have evidence of active HCV infection. This included six members of a single family with familial PCT. Serum samples were screened for antibody to HCV using an enzyme-linked immunosorbent assay. Test results were positive in one patient, but amplification of HCV RNA followed by Southern blotting and hybridizing
. . . [Full Text PDF of this Article]
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