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Leopoldo Borrego, MD; Isabel Castro, MD; Adela Francés, MD; Carmen Gimeno; Elena Soler, MD

Arch Dermatol. 1996;132(10):1157-1158.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

A 28-year-old heterosexual man was found to be seropositive for the human immunodeficiency virus (HIV) in 1990. The patient had recurrent perianal ulcerations and vesicular periungual lesions that were treated with intermittent courses of oral acyclovir. His clinical history was relevant for oral candidiasis. Medications taken included didanosine, sulfamethoxazole, trimethoprim, fluconazole, and ethambutol hydrochloride.

When the patient was seen initially in November 1994, the painful perianal ulceration was persistent for the previous 2 months and unresponsive to oral acyclovir treatment. The 18-cm perianal ulcer had a vesicular border (Figure 1). The CD4 cell count was 0.08x 10⁹/L (80/µL). Initial treatment consisted of intravenous acyclovir (10 mg/kg for 8 hours for 21 days) without result.

The skin biopsy taken from the active border of the lesion showed the presence of epidermal multinucleated giant cells and intranuclear inclusions consistent with herpes simplex virus (HSV) infection, without . . . [Full Text PDF of this Article]

Author Affiliations
Hospital Insular, Las Palmas de Gran Canaria, Spain

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