
Pulsed Dye Laser-Resistant Port-wine Stains
Kay S. Kane, MD
Boston, Mass
Bruce R. Smoller, MD
Stanford, Calif
Richard E. Fitzpatrick, MD
San Diego, Calif
Neil P. J. Walker, FRCP
London, England
Jeffrey S. Dover, MD, FRCPC
Department of Dermatology Harvard Medical School Division of Dermatology New England Deaconess Hospital 110 Francis St, 7H Boston, MA 02215
Arch Dermatol. 1996;132(7):839-841.
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Port-wine stains (PWSs) are congenital lesions characterized by ectatic vessels in the superficial dermis. The cause of these lesions is unknown, but 1 theory is that they result from a diminished neural regulation of the blood flow, secondary to a reduced number of perivascular nerves,1 which, in turn, results in erythrostasis and progressive vessel ectasia. The use of pulsed dye lasers is currently the treatment of choice for PWSs. The 577-nm or 585-nm wavelength selectively targets oxyhemoglobin and the 450-microsecond pulse duration is sufficient to cause intravascular coagulation without excessive heat dissipation to the epidermis or adjacent dermal structures.
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