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  Vol. 132 No. 9, September 1996 TABLE OF CONTENTS
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Nonhealing Leg Ulcer

Ira A. Pion, MD; Mary Ruth Buchness, MD; Henry W. Lim, MD

Arch Dermatol. 1996;132(9):1105-1106.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

A 40-year-old Chinese-American man was in good health until 4 years before presentation, when a tender, enlarging ulcer developed on his right knee. A biopsy was performed at another institution, and a diagnosis of pyoderma gangrenosum was made. The patient was treated with prednisone (120 mg/d), and the ulcer gradually healed; however, it recurred soon after the prednisone therapy was discontinued. Thereafter, the patient was treated with various combinations of prednisone, dapsone, clofazimine, azathioprine, and cyclosporine, along with topical cromolyn and antimicrobials. The ulcer waxed and waned but never completely healed.

Examination of the patient's skin revealed a 10x14-cm ulcer on the lateral aspect of the right knee, extending down to muscle, with undermined borders and a surrounding violaceous rim (Figure 1). Two satellite ulcers (4x3 cm and 1.2x1 cm) were present. There was no enlargement of lymph nodes, liver, or spleen. A right footdrop . . . [Full Text PDF of this Article]


Author Affiliations

New York Veterans Affairs Medical Center and New York University School of Medicine



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