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S. Elizabeth Whitmore, MD
Department of Dermatology The Johns Hopkins Medical Institutions 550 N Broadway, Suite 1002 Baltimore, MD 21205

Arch Dermatol. 1997;133(11):1460-1461.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The retrospective cross-sectional analysis by Dunn et al¹ in a recent issue of the ARCHIVES demonstrates the difficulties confronted when performing an analysis of data that were collected years earlier and not intended to answer the question at hand. For reasons of study design, it is difficult to determine the significance of the analytical results of this study. Because the examination survey by Dunn et al subjectively assessed skin surface appearance only, it is also difficult to compare the results with those of previous studies that have objectively evaluated non—sun-exposed site skin thickness.

The study of 3835 postmenopausal women participating in the First National Health and Nutrition Examination Survey examined the relationship of estrogen replacement therapy and surface skin appearance. Between 1971 and 1974, these women underwent complete skin examinations performed by dermatology residents. As part of this examination, residents noted the presence of skin atrophy, senile dryness, and . . . [Full Text PDF of this Article]

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