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Photodynamic Therapy of Superficial Basal Cell Carcinoma by Instillation of Aminolevulinic Acid and Irradiation With Visible Light
Regina Fink-Puches, MD;
Peter Wolf, MD;
Helmut Kerl, MD
Arch Dermatol. 1997;133(12):1494-1495.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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REPORT OF A CASE
A 63-year-old man presented with a large, 4-cm, superficial basal cell carcinoma (BCC) on the right side of the lower part of his back that had been present for 5 years (Figure, A). He refused surgical intervention.
THERAPEUTIC CHALLENGE
We needed an effective nonsurgical treatment modality for this large BCC.
SOLUTION
After giving his signed consent, the patient was treated with intralesional -aminolevulinic acid (ALA) photodynamic therapy (PDT). Two milliliters of 10% ALA in a 0.9% sodium chloride solution was injected intralesionally with a syringe. After light-shielding occlusion for 4 hours, visual evaluation of the treated lesion under Wood light in a darkened room revealed the typical red fluorescence of porphyrin limited to the tumor (Figure B). The lesion was then exposed to 180-J/cm2 fullspectrum visible light produced by a slide projector (Leica P-2000, Leica, Leitz Wetzlar, Germany) equipped with a 250-W lamp. There was
. . . [Full Text PDF of this Article]
Author Affiliations
Department of Dermatology, University of Graz, Graz, Austria
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