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Celeste Lebbé, MD
Policlinique de Dermatologie Hôpital St-Louis 1 Ave C1 Vellefaux 75010 Paris, France

Claire Pellet; Béatrice Flageul, MD; Xavier Sastre, MD
Paris

Marie Françoise Avril, MD
Villejuif, France

Douceline Bonvalet, MD; Patrice Morel, MD; Fabien Calvo, MD
Paris

Arch Dermatol. 1997;133(7):919-920.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A new virus, human herpesvirus 8 (HHV-8), has recently been associated with Kaposi sarcoma (KS), body cavity—based lymphoma, and Castleman disease.¹ Using polymerase chain reaction (PCR) with the KS330₂₃₃ primers, HHV-8 sequences were detected in an angiosarcoma specimen from a 63-year-old woman who was seronegative for the human immunodeficiency virus,² in 4 cases of angiolymphoid hyperplasia and eosinophilia,³ in 7 of 24 angiosarcomas, and in 1 of 20 hemangiomas.⁴ Other authors^5,6 have failed to demonstrate evidence of HHV-8 in various vascular lesions from Japanese or Chinese patients, including hemangiomas, hemangiopericytomas, pyogenic granulomas, and cutaneous or visceral angiosarcomas. However, a lack of test sensitivity could account for these negative results since they were obtained from parraffin-embedded tissues using a simple PCR. Taking into account these controversial findings, our aim was to obtain further data on the presence of HHV-8 in benign or malignant non-KS vascular . . . [Full Text PDF of this Article]

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