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THE ROSE BENGAL TEST FOR LIVER FUNCTIONWITH PARTICULAR REFERENCE TO ITS USE IN THE THERAPY OF SYPHILIS
N. N. EPSTEIN, M.D.;
J. E. RAUSCHKOLB, M.D.
Arch Derm Syphilol. 1926;14(2):122-135.
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Recent advances made in the study of the functional activity of the liver, by means of various tests, have stimulated the interest of the entire medical profession. Of particular note, perhaps, has been the use of dyes which are eliminated solely by the liver through the bile passages. The dyes used for this purpose include phenoltetrachlorphthalein, rose bengal, bromsulphalein, indigo carmine, methylene blue, congo red and others. Of this number, phenoltetrachlorphthalein and rose bengal have been more thoroughly investigated and have lent themselves to clinical use.
It is but natural that the syphilologist should be among the first to determine the efficiency of these tests because of the frequency of hepatic complications seen in the syphilitic clinic. Rosenthal1 reports that cases of jaundice were eight and eight-tenths more frequent in the syphilitic clinic at Johns Hopkins Hospital than in the medical clinic during the same period. In this work
. . . [Full Text PDF of this Article]
Author Affiliations
CLEVELAND
From the Department of Dermatology and Syphilology of the Western Reserve University Medical School and the Cleveland City Hospital.
Footnotes
Read before the Section on Dermatology and Syphilology at the Seventy-Seventh Annual Session of the American Medical Association, Dallas, Texas, April, 1926.
The rose bengal used in this work was obtained from the National Aniline and Chemical Co., Inc., Pharmaceutical Division, New York.
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