This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GEORGE PINESS, M.D.; HYMAN MILLER, M.D.

Arch Derm Syphilol. 1926;14(2):145-157.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Included as a phase of immunity is a contrary state, namely, anaphylaxis, in which the defense mechanism of the body assumes a destructive character. Immune reactions of the body are commonly brought about by the action of and find expression in the elaboration of substances of a protein nature, antigen and antibody. The same holds true in certain self-destructive reactions of the body, such as anaphylaxis. On this common basis of protein reaction the concept of anaphylaxis has come to be regarded as a phase of immunity.

However, both clinically and experimentally many reactions have been observed of a nature similar to anaphylaxis in which proteins apparently take no part. To include these nonprotein reactions and at the same time to emphasize their essential similarity to protein reactions, von Pirquet¹ in 1905 coined a new word, "allergy," which he defined as "an altered reactivity." As is evident, this definition . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?