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THE EFFECT OF GENTIAN VIOLET ON THE ORGANISM OF BLASTOMYCOTIC INFECTION
EVERETT S. SANDERSON, Ph.D.;
DUDLEY C. SMITH, M.D.
Arch Derm Syphilol. 1927;16(2):153-155.
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The inhibitory effect of gentian violet on gram-positive bacteria,1 and the use of this principle in the isolation of pathogenic molds2 and in the treatment in selected cases of infections resulting from these organisms, have been emphasized by Churchman and others. More recently it has been shown3 that a similar inhibition, both in vivo and in vitro, is elicited against the thrush fungus. The results herewith reported indicate that the selective action of this dye can be extended to include the closely related yeastlike organism of blastomycosis.
The strain used in these tests was recently isolated from the pus in a fatal case of systemic blastomycosis. It was strongly gram-positive, and its morphologic and cultural characteristics were similar to those described by other writers. Fortunately, it was possible to retain this organism in the yeast or budding form for several generations, and the tests were made on
. . . [Full Text PDF of this Article]
Author Affiliations
CHARLOTTESVILLE, VA.
From the Department of Pathology and Bacteriology, and the Department of Dermatology and Syphilology, School of Medicine, University of Virginia.
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