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CLINICAL EXCRETION OF MERCURY11. AFTER INTRAMUSCULAR INJECTIONS OF MERCURIC BROMIDE, AFTER SIMPLE AND AFTER CLEAN INUNCTION
H. N. COLE, M.D.;
JOHN A. GAMMEL, M.D.;
J. E. RAUSCHKOLB, M.D.;
NORA SCHREIBER, B.S.;
TORALD SOLLMANN, M.D.
Arch Derm Syphilol. 1928;17(5):625-647.
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As was pointed out in the first paper of this series the quantitative excretion of mercury is an important index of the concentration of active mercury in the tissues, and should therefore furnish data for the rational administration of mercury. A number of studies on this subject have been published, but they are not conclusive, mainly because the material was not sufficiently extensive to judge and to take account of the natural variability. Some of the studies also disregard the feces, a factor which might be important; and some of the analytic methods appeared rather questionable, at least theoretically.
We found the subject difficult; but with the collaboration of the staffs and resources of the chemistry department of Adelbert College, the department of experimental medicine, the school of pharmacy, the departments of dermatology and syphilology of Lakeside and City Hospitals and the department of pharmacology, we have been able to
. . . [Full Text PDF of this Article]
Author Affiliations
CLEVELAND
From the Departments of Dermatology and Syphilology and of Pharmacology of Western Reserve University, with the collaboration of Lakeside and City Hospitals.
Footnotes
Read before the Section on Dermatology and Syphilology at the Seventy-Eighth Annual Session of the American Medical Association, Washington, D. C., May 19, 1927.
The expenses of this investigation have been met mainly by the Lakeside Hospital and by a grant from the Therapeutic Research Committee of the Council on Pharmacy and Chemistry of the American Medical Association.
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