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LI.—SOME BIOLOGIC FACTORS IN THE STUDY OF CANCER, WITH SPECIAL REFERENCE TO THEIR RELATIONSHIP TO PRECANCEROUS LESIONS OF THE SKIN
LOUIS H. JORSTAD, M.D.
Arch Derm Syphilol. 1928;18(3):351-367.
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In 1910, Burrows1 took up the study of cellular growth in vitro. Harrison2 had studied the behavior of the isolated central nervous system, as well as other tissues of young frog embryos in hanging drops of fluid lymph obtained from the lymph sac of this animal. This lymph was not a good medium for cellular growth, thus Burrow's problem was that of obtaining a suitable one, so that cells of different types might be grown in vitro. Harrison was unable to obtain a growth of cells. He had obtained a growth of nerve fibers and a migration of the cells, but multiplication of the cells was not obtained. Burrows undertook to see if the cells could not be cultivated under some such similar conditions. The lymph which Harrison had used was not a good medium in that it could not be obtained readily from higher animals and it
. . . [Full Text PDF of this Article]
Author Affiliations
ST. LOUIS
From the Research Laboratories of the Barnard Free Skin and Cancer Hospital.
Footnotes
Studies, observations and reports from the dermatologic departments of the Barnard Free Skin and Cancer Hospital and the School of Medicine, Washington University, St. Louis, Mo., service of Drs. M. F. Engman and W. H. Mook.
Read before the Annual Meeting of the Mississippi Valley Dermatological Society, Nov. 19, 1927.
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