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A HISTOLOGIC STUDY ESPECIALLY DIRECTED TOWARD THE STUDY OF MELANOBLASTS

S. WILLIAM BECKER, M.D.

Arch Derm Syphilol. 1930;21(5):818-835.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Pigmented malignant neoplasms are among the most serious tumors afflicting mankind. They are fortunately rare, which fact has militated against a clearer conception of their origin and nature. Ewing¹ stated: "The peculiar and obscure conditions of its origin, the remarkable physiologic properties of the chromatophores (melanoblasts—author) in the animal kingdom, the eccentricities of its clinical course and its interesting history as a field of debate render this tumor one of the most notable topics in oncology." Many authors have written on this subject, more recently Dawson² and Miescher.³ Difficulties in interpretation on solely morphologic grounds have been partially overcome by the functional approach to the problem of melanin pigmentation, which phase of biologic activity lends itself well to study, since it furnishes a visible end-point.

NORMAL PIGMENTATION

Consideration of the pigment problem may be found in recent publications.⁴ The salient features may be briefly summarized. Cutaneous . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Division of Dermatology of the Department of Medicine of the University of Chicago.

Footnotes
Submitted for publication, Oct. 11, 1929.

Read before the Section on Dermatology and Syphilology at the Eightieth Annual Session of the American Medical Association, Portland, Ore., July 12, 1929.

The publication of this work has been aided by a grant from the Douglas Smith Foundation for Medical Research at the University of Chicago.

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