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THE CLINICAL VALUE OF BISMARSEN IN THE TREATMENT FOR SYPHILIS
CHARLES H. DE T. SHIVERS, M.D.
Arch Derm Syphilol. 1930;22(3):462-469.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Bismarsen, or bismuth arsphenamine sulphonate, is a new drug synthesized by Dr. George W. Raiziss and tested clinically for the first time early in 1925. According to Raiziss, the empiric formula is C21 H21 O12 As3 Na3 S3 N3 Bi2; the arsenic content varies from 12 to 15 per cent and the bismuth from 23 to 25 per cent.
The drug thus combines two of the most efficient antisyphilitic agents in one preparation, and has won for itself a place in syphilotherapy because of its spirillicidal and defense arousing properties, its low foxicity and absence or mildness of local reactions combined with stability and ease of administration.
Injections are made by the intramuscular route only, and my associates and I have obtained the best results with a dosage of 0.2 Gm. once a week as a secondary course in the treatment for
. . . [Full Text PDF of this Article]
Author Affiliations
Associate Professor of Syphilology, Graduate School of Medicine, University of Pennsylvania; Chief Urologist, Atlantic City Hospital, and Atlantic City Genito-Urinary Clinic ATLANTIC CITY, N.
Footnotes
Submitted for publication, March 12, 1930.
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