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CLINICAL EXCRETION OF BISMUTHPOTASSIUM BISMUTH TARTRATE AND BISMUTH SALICYLATE
P. J. HANZLIK, M.D.;
H. G. MEHRTENS, M.D.;
D. C. Marshall, M.D.;
Frances Watson, A.B.;
Jean Spaulding, A.M.
Arch Derm Syphilol. 1930;22(4):605-614.
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This paper presents the excretory results with potassium bismuth tartrate and bismuth salicylate as those with bismuth metal were presented in a previous paper.1 The two products are discussed together because both are administered in oil, although the potassium bismuth tartrate is water-soluble and the bismuth salicylate is practically insoluble in both water and oil. The bismuth content of the potassium bismuth tartrate used was 56 per cent, and that of the bismuth salicylate, 60 per cent, by analysis. The methods of analysis for bismuth have been described for the entire group of products in a previous communication1 and will be omitted here. Both products were administered into the gluteal musculature in confined patients with and without syphilis. Excretory results were obtained from a total of six subjects the data being nearly or fairly complete on four subjects, that is, two receiving each product.
URINARY EXCRETION
Urinary excretion
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO
From the Department of Pharmacology and the Neuropsychiatric Division of the Department of Medicine, Stanford University School of Medicine.
Footnotes
Submitted for publication, May 3, 1930.
This study was supported by a grant from the Committee on Research in Syphilis, Inc.
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