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COMPARISON WITH ARSPHENAMINE

GEORGE W. RAIZISS, Ph.D.; MARIE SEVERAC, M.D.

Arch Derm Syphilol. 1933;28(3):389-396.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

While the discovery of the arsphenamines by Ehrlich in 1906 was one of the greatest single advances in the field of medicine in general and in that of chemotherapy in particular, it would be vain to pretend that the problem of the effective treatment of syphilis in all its manifestations has thereby been completely solved. The need for further additions to the weapons of the syphilologist, and especially for measures tending toward simplification of treatment and elimination of reactions, does not require emphasis; our purpose is rather to attempt to evaluate, on the basis of experimental studies with syphilitic rabbits, the efficiency of one compound, bismarsen, synthesized by one of us (G. W. R.) in 1924.

Bismarsen is the result of an attempt to combine in one molecule two of the best spirocheticidal elements, arsenic and bismuth. It is the sodium salt of a bismuth derivative of arsphenamine methylene sulphonic . . . [Full Text PDF of this Article]

Author Affiliations
Professor of Chemotherapy, Graduate School of Medicine, University of Pennsylvania; PHILADELPHIA

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