This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

P. J. HANZLIK, M.D.; H. G. MEHRTENS, M.D.; J. B. SPAULDING, A.M.

Arch Derm Syphilol. 1934;29(2):298-306.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This paper presents the final results on the urinary and fecal excretion of bismuth after the administration of iodobismitol in man and in animals. Since the publication of a preliminary report,¹ the number of subjects for this study has been increased, the total number of human beings being twenty-two, and the number of rabbits, thirteen. For one reason or another, not all human beings and animals permitted the study of complete excretion. Satisfactorily completed excretions were obtained with ten persons and seven rabbits.

METHODS

The iodobismitol was injected intramuscularly in both patients and rabbits. The iodobismitol contained 6 per cent sodium iodobismuthite (containing 21.5 per cent bismuth) and 12 per cent sodium iodide in ethylene glycol (description in "New and Nonofficial Remedies"). The doses used were of therapeutic order, ranging from a single dose of 0.033 cc. per kilogram (2 cc. for an adult weighing 60 Kg.) to multiple . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Department of Pharmacology and the Neuropsychiatric Division of the Department of Medicine, Stanford University School of Medicine.

Footnotes
The clinical part of this work was due largely to the encouragement of Dr. Henry George Mehrtens, whose premature death on Feb. 28, 1933, deprived us of an inspiring and loyal colleague.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?