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HENRY E. MICHELSON, M.D.; FRANCIS W. LYNCH, M.D.

Arch Derm Syphilol. 1934;29(6):805-820.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Systematized amyloidosis is the name which Lubarsch proposed for a form of amyloidosis which was atypical for generalized amyloidosis, but which involved far too much tissue to be classed as a localized form. The cases of systematized amyloidosis observed by Lubarsch¹ had certain features in common, thus establishing a fairly well defined syndrome; but specific cutaneous manifestations were not constant, although they were present in a high percentage of the patients observed.

Generalized amyloidosis, as originally described, consisted of changes in the large abdominal viscera accompanying such diseases as syphilis, tuberculosis, blastomas and some chronic suppurations. These diseases apparently have the faculty of altering protein metabolism in such a way as to produce amyloid.

Atypical deposits of amyloid were soon recognized, and Ziegler² called attention to the most common form when, in 1875, he demonstrated amyloid deposits strictly limited to the tongue and larynx. Such isolated involvement has . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

From the Division of Dermatology, University of Minnesota.

Footnotes
Read at the Fifty-Sixth Annual Meeting of the American Dermatological Association, Chicago, June 9, 1933.

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