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A COMPARISON OF THE WASSERMANN AND SACHSGEORGI REACTIONS IN THE SEROLOGIC DIAGNOSIS OF SYPHILIS
ROBERT A. KILDUFFE, A.M., M.D.
Arch Derm Syphilol. 1921;3(4 PART 1):415-420.
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Since the introduction of the Wassermann test as a serologic method of diagnosis in syphilis in 1906, the reaction has been the subject of extensive and intensive study, particularly as concerns its mechanism and the standardization of its technic.
The fact that we are still in doubt as to an exact and definite understanding of the mechanism whereby the reaction occurs; that the exact nature of the body whose presence in syphilitic serum gives rise to the reaction is still a matter of uncertainty; and, above all, the clear and evident necessity for a thorough understanding of the principles of the test, in so far as they are known, and of the many niceties of technic which must be mastered and understood before one is competent to perform and interpret the test—all these have given an added impetus to numerous attempts to simplify the reaction and render it available to
. . . [Full Text PDF of this Article]
Author Affiliations
Director of Laboratories, Pittsburgh Hospital PITTSBURGH
From the Laboratories of the Pittsburgh Hospital.
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