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Samuel Feldman, M.D.
New York

Arch Derm Syphilol. 1936;33(3):542.

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To the Editor.—I wish to report a further observation on a patient whose case was described in the ARCHIVES in the September 1934 issue (page 415). A statement was made in that paper that the patient was sensitive to all forms of trivalent arsenic and was able to tolerate quinquivalent arsenical preparations only. As a matter of fact, there was no other form of trivalent arsenic other than the arsphenamine group which was available for the treatment of syphilis at that time. Since then, mapharsen (the hemialcoholate of 3-amino-4-hydroxyphenylarsine oxide hydrochloride) has been introduced. The patient is now being treated with that drug, and she shows no signs of intolerance to it. This proves that the allergy in that case was specific for the arsphenamine group and not for all trivalent arsenical preparations.

Correspondence . . . [Full Text PDF of this Article]

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