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H. HANFORD HOPKINS, M.D.; EARL L. BURKY, M.D.

Arch Derm Syphilol. 1936;33(6):1060-1061.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since 1906 it has been known that filtrates from broth cultures of certain strains of staphylococcus contain a specific exotoxin.¹ On this fact, however, general attention was not focused until 1928,² when in Bundaberg, Australia, twelve children died after receiving injections of diphtheria antitoxin, which later was shown to have been contaminated with a toxin producing staphylococcus. In 1930 Burky³ isolated similar staphylococci from various cutaneous lesions, and he, as well as others, has published studies dealing with this toxin.⁴

In order to determine the reactivity of the skin to this toxin shown by patients with various types of cutaneous diseases, we have performed intracutaneous tests on ninety-seven patients from the dermatologic dispensary. The test dose of toxin (Burky's) was 0.1 cc. of a 1:100 dilution, injected intracutaneously in the forearm. Reactions were observed forty-eight hours later.

The purpose of this paper is to . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Dermatological Clinic of the Johns Hopkins Hospital and the Wilmer Ophthalmological Institute of the Johns Hopkins University and Hospital.

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