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TRICHOPHYTIN AND ALLERGY TO TRICHOPHYTINI. COMPARISON OF CUTANEOUS RESPONSES TO TWO STANDARD PREPARATIONS OF TRICHOPHYTIN AND TO DERMATOMYCOL (DA FONSECA AND DE ARÊA LEÃO)
MARION B. SULZBERGER, M.D.;
GEORGE M. LEWIS, M.D.;
FRED WISE, M.D.
Arch Derm Syphilol. 1936;34(2):207-217.
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Clinical and laboratory studies in trichophytin allergy, including experiments in sensitization, hyposensitization and immunization, have received attention for three reasons: (1) because of the influence of these phenomena on the course of mycotic infections, including their possible therapeutic effect on certain fungous diseases; (2) because of their general significance in the theoretical conceptions of immune biology, and (3) because trichophytin belongs to a large and universally important group of allergens of practical significance in infectious diseases (e. g., tuberculin, luetin, the Frei vaccine, leprolin, mallein, sporotrichin, oidiomycin and tularemia vaccine).
For the two reasons last mentioned, studies and experiments with trichophytin merit attention far beyond that which might be accorded them if their results were applicable only to fungous diseases. There are such close analogies, particularly between trichophytin and tuberculin allergy, that it may be stated that what is done with trichophytin may usually be repeated
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK With the Assistance of Mary E. Hopper, M.S.
From the Skin and Cancer Unit, the New York Post-Graduate Medical School and Hospital, service of Dr. Fred Wise, Dr. George M. MacKee, Director.
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