This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

E. WILLIAM ABRAMOWITZ, M.D.; MAURICE H. NOUN, M.D.

Arch Derm Syphilol. 1937;35(5):875-892.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

We believe that the term fixed drug eruption as first applied and interpreted by Brocq is not always employed in the original sense. As a help to a better understanding of such eruptions we are restating the definition of the term fixed so far as it applies to drug eruptions. We submit also a compilation of the different types of fixed eruptions that have been reported, the various drugs and other agents considered responsible for them and some comments on the pathogenesis of such manifestations.

HISTORICAL NOTES

Soon after 1885, when antipyrine came into use, several observers called attention to eruptions caused by this drug. One type noted was peculiar in that it recurred at the previously affected areas of the skin whenever antipyrine was again ingested.

Brocq¹ after observing several cases, designated such cutaneous manifestations as fixed. His description may be summarized as follows: The cutaneous manifestations appeared . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK; DES MOINES, IOWA

From the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital, Columbia University, Dr. George M. MacKee, Director.

Footnotes
Read before the Section on Dermatology and Syphilology at the Eighty-Seventh Annual Session of the American Medical Association, Kansas City, Mo., May 14, 1936.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?