This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

J. F. BURGESS, M.D.; I. M. RABINOWITCH, M.D.

Arch Derm Syphilol. 1937;35(5):932-941.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This study was undertaken to test the possibility that defective hepatic function may be a factor in the production of certain dermatoses. As is well known, the liver is interposed between the gastro-intestinal tract and the general circulation, and one of its functions is to prevent toxic substances from the gastro-intestinal tract from entering the blood stream. This is accomplished, to a large extent, by detoxification, the processes of which include oxidation, reduction and conjugation. Theoretically, therefore, failure of this function of the liver might permit entry of toxic substances into the general circulation and thus lead to their deposition in the skin. That defective hepatic function may be a factor is suggested by the frequent occurrence of cutaneous lesions in cases of diabetes, a disease in which disturbances of hepatic function have been found to be common.¹

A difficulty of putting the aforementioned possibility to the test of . . . [Full Text PDF of this Article]

Author Affiliations
MONTREAL, CANADA

From the Departments of Dermatology and Metabolism, the Montreal General Hospital.

Footnotes
Read at the Fifty-Ninth Annual Meeting of the American Dermatological Association, Inc., Swampscott, Mass., June 5, 1936.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?