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By Robert Simons. Pp. 50. Leyden: A. W. Sijthoff.

Arch Derm Syphilol. 1937;36(6):1312.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The author investigated the effect of arsenical medication in 160 cases of psoriasis. Arsenic was administered as arsenic trioxide in pills containing from 1 to 5 mg., given 3 times daily, and as solution of potassium arsenite in doses of from 5 to 25 drops, 3 times daily. Signs of intoxication, such as conjunctivitis, diarrhea, nausea and weakness, were not considered indications for reducing the dose or discontinuing treatment unless they were severe.

The results of this investigation led the author to conclude that treatment with inorganic arsenic does not effect permanent cure of psoriasis. Temporary involution can be produced, but this is of short duration and accompanied by signs of intoxication. Recurrence cannot be prevented by resumption of the arsenical medication. In about 30 per cent of the cases new lesions of psoriasis appeared during treatment. With few exceptions, all the patients showed signs of arsenical intoxication, particularly when . . . [Full Text PDF of this Article]

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