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ALBERT R. McFARLAND, M.D.; WILLIAM H. STRAIN, Ph.D.

Arch Derm Syphilol. 1938;38(5):727-736.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the group of dermatoses in which photosensitivity is present it has been, generally speaking, impossible to find a cause for the sensitivity. In the rare condition hydroa aestivale with congenital porphyria, however, it seems probable that the cutaneous manifestations are due to sensitization produced by the porphyrins, though other factors, doubtless, are involved. It is known that sensitivity to light can be experimentally produced in the lower organisms, in animals and in man by the injection of porphyrins prior to exposure to sunlight. It therefore occurred to us that a study of the excretion of porphyrin in a variety of dermatoses in which there seemed to be light sensitivity clinically might be of interest. With this in view, we determined the level of excretion of the ether-soluble porphyrins in the urine of persons with a variety of dermatoses, most of which had a photosensitive aspect. Before we consider the . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, N. Y.

From the Department of Medicine, School of Medicine and Dentistry, and Strong Memorial Hospital, the University of Rochester.

Footnotes
Read at the Sixty-First Annual Meeting of the American Dermatological Association, Inc., Del Monte, Calif., June 10, 1938.

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