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PIGMENTARY EFFECTS OF ANTHRALIN (DIHYDROXYANTHRANOL) IN TWO CASES OF ALOPECIA AREATA

M. H. GOODMAN, M.D.

Arch Derm Syphilol. 1939;40(1):76-81.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Dihydroxyanthranol-1, 8, under the trade name cignolin, was introduced into dermatology in 1916 by Galewsky¹ and Unna,² who stressed its value as a substitute for chrysarobin in the treatment of psoriasis. Beerman and his collaborators,³ in reporting on this chemical, known in America by the name anthralin, in 1935, discussed its properties and its successful employment in the treatment of a number of dermatoses and especially emphasized its use in low concentrations (from 0.1 to 1 per cent) with relatively little irritating effect even when applied to the scalp or face. They referred to its effectiveness for alopecia areata and stated that in some cases they obtained a better effect by combining its use with ultraviolet irradiation. In the discussion of this report it was brought out that the beneficial effects on certain cutaneous conditions of chrysarobin, dihydroxyanthranol and anthrasol are, as in the case of coal . . . [Full Text PDF of this Article]

Author Affiliations
Instructor in Dermatology, Johns Hopkins University School of Medicine BALTIMORE

From the Department of Dermatology, Johns Hopkins Hospital.

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