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SYNTHETIC TAR PASTEA Therapeutic Suggestion
W. H. Guy, M.D.;
F. M. Jacob, M.D.;
Frank Weber, Ph.G.
Arch Derm Syphilol. 1939;40(1):90-91.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The efficacy of crude coal tar as a topical application is attested by the favorable clinical experience of dermatologists throughout the world. Patients object to its uncleanliness and staining qualities. Furthermore, different lots of crude coal tar vary materially in composition. Feeling that a preparation free of these objectionable qualities and with equivalent therapeutic effect would be distinctly advantageous, we have elaborated a synthetic tar by ascertaining the average formula of crude coal tar and eliminating inert and irritating substances, a classification which, as will be noted, includes 44.7 per cent pitch.
Using these figures as a guide, we have prepared a synthetic tar containing quantities of active ingredients equivalent to those contained in the original coal tar, the ratio being corrected in keeping with elimination of the inert substances and the irritating light oils.
The formula just given may be used in various preparations in the same percentages as crude coal tar. The following formula is one we frequently use:
. . . [Full Text PDF of this Article]
Author Affiliations
Pittsburgh
From the Department of Dermatology of the University of Pittsburgh School of Medicine.
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