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FAILURE WITH WELL CONTROLLED ADMINISTRATION

JOHN F. WILSON, M.D.

Arch Derm Syphilol. 1939;40(2):241-243.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In view of a recent report and discussions¹ of the action of sulfanilamide in cases of acute disseminated lupus erythematosus, it is of interest that in a case of typical involvement in which the streptococcus was cultured from the lesions well controlled sulfanilamide therapy produced no improvement.

In May 1937 sulfanilamide was used in a case of acute disseminated lupus erythematosus² in the students' health service at the University Hospitals. Administration was discontinued, however, because of severe reactions. Necropsy showed miliary tuberculosis.

Because of the activity of sulfanilamide against the beta hemolytic streptococcus, the drug was used in the case to be reported. As efficiency results when a minimum level of 10 mg. of sulfanilamide per hundred cubic centimeters of blood is maintained, this concentration was exceeded throughout the course.

REPORT OF A CASE

Mrs. M. B., a white woman aged 31, suffered a severe sunburn in July . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

From the Division of Dermatology, University of Minnesota, Henry E. Michelson, M.D., Director.

Footnotes
The autopsy was performed by Dr. Lawrence Berman.

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