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STAPHYLOCOCCUS AMBOTOXOIDEXPERIENCE WITH ITS USE IN THE TREATMENT OF ACNE VULGARIS AND OTHER PYOGENIC DERMATOSES
LEONARD E. ANDERSON, M.D.;
JOHN H. STOKES, M.D.
Arch Derm Syphilol. 1939;40(3):382-385.
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Immunologic treatment of various dermatoses has been attempted in the past with varying success, and both specific and nonspecific biologic preparations have been employed. Because the use of a staphylococcus toxoid appeared rational in the treatment of furunculosis and other pyogenic dermatoses, we undertook to study the effect produced by such treatment in a series of patients in our private practice whose lesions were proving resistant to the ordinary therapeutic procedures.
The study was begun with a staphylococcus toxoid prepared from multiple strains of toxin-producing staphylococci according to the technic of Dolman,1 as described by Leonard and Holm.2 Thirteen courses of treatment with this toxoid were included in this study. Later a preparation was used which combined the aforementioned type of staphylococcus toxoid with a bacterial antigen.3
Only furunculosis and pustular acne vulgaris were treated at first, but later other miscellaneous dermatoses were included because we felt
. . . [Full Text PDF of this Article]
Author Affiliations
SPRINGFIELD, MASS.; PHILADELPHIA
From the Department of Dermatology and Syphilology, School of Medicine, University of Pennsylvania, John H. Stokes, M.D., Director.
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