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INTRAVENOUS USE IN DIAGNOSIS OF LYMPHOGRANULOMA VENEREUM

DOUGLASS A. DECKER, M.D.; ORLANDO CAñIZARES, M.D.; REUBEN FRANK REIDER, M.D.

Arch Derm Syphilol. 1939;40(3):397-401.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Hellerström¹ in 1931 first reported that the intravenous injection of Frei antigen prepared with human pus was followed by a typical febrile response in patients with lymphogranuloma venereum. A similar reaction was not produced in control subjects. Ravaut, Levaditi and Maisler² injected monkey brain antigen intravenously. They stated that patients with lymphogranuloma venereum react to intravenous injection of antigen while the intradermal Frei test is still negative. Gay Prieto and Egea Bueno³ and Flandin and Turiaf⁴ reported in favor of its diagnostic value. Findlay⁵ expressed the belief that the intravenous test is dangerous. Wlassics⁶ found that 30 per cent of his control subjects, chiefly patients with tuberculosis of the skin, gave a positive reaction.

The difference in the reports of some of the investigators may be accounted for by differences in potency and amount of antigen used. The question of patients with mixed infections . . . [Full Text PDF of this Article]

Author Affiliations
ALLENTOWN, PA.; NEW YORK

From the Department of Dermatology and Syphilology, New York University College of Medicine, and the Dermatologic Service of Bellevue Hospital, service of Dr. Edward R. Maloney.

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