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REPORT OF A CASE

HERMAN A. LEVY, M.D.

Arch Derm Syphilol. 1940;41(4):690-691.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Vasomotor reactions not uncommonly occur to the arsenicals used in the treatment of syphilis, especially to the trivalent arsphenamines. The pentavalent tryparsamide, however, rarely produces ill effects. Moore¹ stated that "visual damage is the only complication of tryparsamide therapy to be feared." With 6,933 injections of tryparsamide given by the medical department of the United States Navy,² only 1 untoward result occurred: a mild exfoliative dermatitis. A thorough search of the literature revealed a paucity of reports of vasomotor reactions to this drug. A suggestive report was that of Miller and O'Donnell,³ whose patient suffered a profound collapse with generalized pallor of the skin, rather than the rubor associated with the so-called nitritoid reaction. Recently, however, Astrachan and Franks⁴ reported a typical nitritoid reaction in a 32 year old woman and also referred to two previous reports.⁵ According to Stokes⁶ and O'Leary,⁷ this . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Medicine, University of Illinois College of Medicine.

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